Basu Lab
Head and Neck Cancer Biology and Translational Therapeutics
Devraj Basu Laboratory
Dept. Otorhinolaryngology - Head and Neck Surgery
University of Pennsylvania Perelman School of Medicine
Philadelphia, PA USA
Varun Sahu, B.S. After graduating from Rutgers University, Mr. Sahu served the lab from 2014 until 2019 as a Research Specialist. In addition to participating in all basic studies in the laboratory, he played a central role in developing the unique patient-derived models now available to the lab, including the multiple PDXs, organoids, and cell lines derived from HPV+ head and neck cancers. He is presently working in the lab of Anil Rustgi, MD at Columbia University and applying to medical school.
Core Members
Malay Sannigrahi, Ph.D. Dr. Sannigrahi joined the lab in December 2018 after finishing his PhD training in cancer biology and virology. His graduate study focused on the role of noncoding RNAs in regulating HPV16-induced oncogenesis in head and neck cancer. Since joining the lab, he has focused on the interplay between diversity in viral oncogene expression, tumor metabolic profile, and therapy resistance in HPV+ cancer.
Lovely Raghav, Ph.D. Dr. Raghav joined the lab in 2022 after completing her graduate degree in Bioinformatics in Taiwan. She has significant prior experience in high throughput genomic, transcriptomic, and proteomic data analysis. Her current project focuses on defining intratumor diversity malignant cell states in HPV+ cancers and identifying the tumor cell states that contribute to resistance of a subset of tumors to therapy. She is also evaluating molecular features that distinguish HPV-related head and neck cancers at high vs. low risk of lethal recurrence after robotic surgery.
Part Time
Theodore Gobillot, M.D, Ph.D. Dr. Gobillot became affiliated with the lab in 2022 after completing his graduate training at the University of Washington and starting Otolaryngology residency training at Penn. He is involved in the projects in the lab relating to clinical and molecular risk stratification for HPV+ head and neck cancer.